Jaks, STATs, Cytokine Signal Transduction, and Immunoregulation: Are We There Yet?
نویسندگان
چکیده
منابع مشابه
"Are we there yet?".
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derivatives suppress TH17 cell differentiation by antagonizing RORgammat activity. Activating mutations in JAK2, a tyrosine kinase that serves as a critical signaling protein for multiple cytokines, are associated with BCR-ABL1–negative myelo-proliferative neoplasms. In this issue of Blood, Zheng and colleagues report that the constitutively activated kinase CK2 binds to JAK2 and is required fo...
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ژورنال
عنوان ژورنال: Immunity
سال: 1997
ISSN: 1074-7613
DOI: 10.1016/s1074-7613(00)80505-1